U.S. HHS Secretary Moves to Overhaul Longstanding GRAS System, Ending Self-Affirmation for Food Ingredients

On March 10, 2025, Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. directed the Food and Drug Administration (FDA) to explore rulemaking to eliminatebest calcium citrate with magnesium the self-affirmed "magnesium malate 400 iherbGenerally Recognized As Safe" (GRAS) pathway. For decades, food manufacturers have been able to self-determine the safety of new ingredients without notifying the FDA, raising concerns about transparency and bayer citracal calcium citrateoversight. ferrous sulfate 65The proposed change would require all enterprises introducing new food ingredients to publicly notify the FDA anferrous fumarate costd provide supporting safety data before marketing their products.

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