India’s Arjuna Natural Extracts is targeting the European market with BCM-95 Curcumin, an all-natural patented formulation of turmeric extract.###The ingredient can help mitigate symptoms of depression and anxiety, according to a recent clinical study, further backed by nearly 24 studies supporting the health benefits of the extract.###The randomized, double-blind, placebo-controlled study of 56 individuals with major depressive disorder was published in June, 2014 by Adrian Lopresti, PhD, et al., of Murdoch University, Australia, in the peer-reviewed Journal of Affective Disorders 167(2014)368–375. ###Results showed that supplemenmagnesium citrate supplementtation with BCM-95 Curcumin succeeded in reducing the overall symptoms of depression, functioning as an anxiolytic as well when taken over eight weeks.###Greater efficacy from curcumin treatment was identified in a subgroup of individuals with atypical depression (common depression).###Thcitracal calcium plus d3ere were no significant differences in the adverse events between BCM-95 and the placebo.###“Curcumin’s positive antidepressant and anti-anxiety effects are likely due to its ability to normalize specific physiological pathways,” says Lopresti. ###“It appears to elevate neurotransmitters such as serotonin, while lowering stress hormones, such as cortisol, and is a potent antioxidant and anti-inflammatory.”###“Curcumin also provides protection to the brain.”##
#Disease burden
Depression is a common, treatable disorder that continues to remain under detected globally. ###Health surveys indicate that major depression is experienced by 10-15% of people in their lifetime. ###The condition is caused by multiple factors and the success rate of current treatment is only 20-40%. ###Many treatments are associated with side effects from long-term use, including anxiety, thoughts of suicide, insomnia, weight gain and sexual dysfuncti
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Curcumin works simultaneously on multiple pathways associated with depression. ###It is considered as the most promising therapeutic targetsca citrate to treat depressive behavior.###BCM-95 curcumin is produced from non-GMO turmeric. ###It has been researched by universities throughout the US, Australia, Japan and India in multiple clinical studies and has attained 12 international patents.###BCM- 95 curcumin is manufamagnesium citrate sam’s clubctured by synergistically combining curcumin and essential oil of turmeric, without synthetic additives. ###The therapeutic benefits of turmeric can be attained at its best by combining curcumin with ar-turmerone, an active compound derived from essential oil of turmeric. ###In BCM-95, this synergy forms a 95% bioactivity enhanced curcuminoid complex to create a highly bioactive turmeric extract with superior bioavailability.